Best Blockchain (2025)

Ranked picks for blockchain. No "it depends."

🧊Nice Pick

Ape Framework

Python's answer to smart contract development. All the blockchain headaches, now with fewer excuses.

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#1

Ape Framework

Nice Pick
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Python's answer to smart contract development. All the blockchain headaches, now with fewer excuses.

Pros

  • +Leverages Python's ecosystem for testing and tooling
  • +Modular plugin system for custom workflows
  • +Built-in support for multiple EVM-compatible chains
  • +Integrated project management and contract compilation

Cons

  • -Python dependency hell can creep in
  • -Still requires deep blockchain knowledge despite the abstraction
#2
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Python's answer to Ethereum development. All the smart contract power, none of the JavaScript fatigue.

Pros

  • +Python-based scripting makes contract interaction intuitive for Python devs
  • +Built-in support for Ganache and Web3.py streamlines local testing
  • +Automates compilation and deployment, reducing boilerplate code

Cons

  • -Limited ecosystem compared to JavaScript-based tools like Hardhat
  • -Can be slower for large projects due to Python's overhead
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Ape Framework vs Brownie

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