DNA Methylation Sequencing
DNA Methylation Sequencing is a high-throughput genomic technique used to map and quantify DNA methylation patterns across the genome at single-base resolution. It involves sequencing bisulfite-treated DNA to detect cytosine methylation, primarily at CpG sites, enabling researchers to study epigenetic modifications. This technology is crucial for understanding gene regulation, cellular differentiation, and diseases like cancer.
Developers should learn DNA Methylation Sequencing when working in bioinformatics, computational biology, or genomics to analyze epigenetic data for research or clinical applications. It is essential for projects involving cancer epigenomics, developmental biology, or biomarker discovery, as it provides detailed insights into methylation landscapes that influence gene expression and disease mechanisms.